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Antigenic Specificity | P16-INK4A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat; |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Please decide the specificity by homology. CDKN2A generates several transcript variants which differ in their first exons. At least three alternatively-spliced variants encoding distinct proteins have been reported, and two are related, named p16-INK4 and p14 respetively, sharing 50% identity. The third one is completely stuctually un-related, called p14(ARF) or p19(ARF). 10883-1-AP reacted with p16 specifically. P16 plays an important role in regulating the cell cycle, and mutations in p16 increase the risk of developing a variety of cancers, notably melanoma. |
Immunogen | Immunogen: Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) |
Other Names | [ARF,CDKN2A, CDK4 inhibitor p16 INK4, CDK4 inhibitor p16INK4, CDK4I, CDKN2, CDKN2A, CMM2, INK4, INK4a, MLM, MTS 1, MTS1, Multiple tumor suppressor 1, p14, p14ARF, P16, p16 INK4, p16 INK4a, p16INK4, p16INK4a, P19, TP16] |
Gene, Accession # | [P16-INK4A], UniProt: P42771 |
Catalog # | MBS7602297 |
Price | $265 |
Order / More Info | P16-INK4A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |