Edit |   |
---|---|
Antigenic Specificity | MAP4K3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAP4K3 antibody is generated from rabbits immunized with a recombinant protein of human MAP4K3. MAP4K3 encodes a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase kinase kinase kinase 3; Germinal center kinase-related protein kinase; GLK; MAPK/ERK kinase kinase kinase 3; MEK kinase kinase 3; MEKKK 3; MAP4K3; RAB8IPL1] |
Gene, Accession # | [MAP4K3], Gene ID: 8491, NCBI: NP_001257354.1, UniProt: Q8IVH8 |
Catalog # | MBS9200692 |
Price | $165, $370 |
Order / More Info | MAP4K3 Antibody from MYBIOSOURCE INC. |
Product Specific References | Yan, L., et al. Mol. Cell 37(5):633-642(2010) Ichikawa, S., et al. J. Bone Miner. Res. (2010) In press : Lam, D., et al. Proc. Natl. Acad. Sci. U.S.A. 106(29):11978-11983(2009) Wu, C., et al. Proteomics 7(11):1775-1785(2007) |