MAP4K3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMAP4K3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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DescriptionThis MAP4K3 antibody is generated from rabbits immunized with a recombinant protein of human MAP4K3. MAP4K3 encodes a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1
Immunogenn/a
Other Names[Mitogen-activated protein kinase kinase kinase kinase 3; Germinal center kinase-related protein kinase; GLK; MAPK/ERK kinase kinase kinase 3; MEK kinase kinase 3; MEKKK 3; MAP4K3; RAB8IPL1]
Gene, Accession #[MAP4K3], Gene ID: 8491, NCBI: NP_001257354.1, UniProt: Q8IVH8
Catalog #MBS9200692
Price$165, $370
Order / More InfoMAP4K3 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesYan, L., et al. Mol. Cell 37(5):633-642(2010) Ichikawa, S., et al. J. Bone Miner. Res. (2010) In press : Lam, D., et al. Proc. Natl. Acad. Sci. U.S.A. 106(29):11978-11983(2009) Wu, C., et al. Proteomics 7(11):1775-1785(2007)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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