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Antigenic Specificity | NONO |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NONO is DNA- and RNA binding protein, involved in several nuclear processes. It binds the conventional octamer sequence in double stranded DNA. It also binds single-stranded DNA and RNA at a site independent of the duplex site. It is involved in pre-mRNA splicing and interacts with U5 snRNA. The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclear retention of defective RNAs, be involved in DNA unwinding by modulating the function of topoisomerase I/TOP1 and be involved in DNA nonhomologous end joining required for double-strand break repair and VJ recombination and may stabilize paired DNA ends. NONO binds to an enhancer element in long terminal repeats of endogenous intracisternal A particles and activates transcription. |
Immunogen | Immunogen: NONO antibody was raised in Rabbit using synthetic peptide of human NONO as the immunogen. |
Other Names | [Rabbit NONO; NONO; NONO; Octamer-binding; NRB54; NMT54; Non-POU Domain Containing; P54NRB; Nuclear RNA-binding protein] |
Gene, Accession # | [NONO], Gene ID: 4841 |
Catalog # | MBS5311451 |
Price | $430 |
Order / More Info | NONO Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |