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Antigenic Specificity | TNNI2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 100ug/100ul |
Applications | Peptide ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein als |
Immunogen | Immunogen: Synthetic peptide conjugated to KLH |
Other Names | [Homo sapiens troponin I type 2 (skeletal, fast) (TNNI2), transcript variant 1, mRNA; Troponin I, fast skeletal muscle; troponin I, fast skeletal muscle; troponin I fast twitch 2; troponin I, fast-twitch isoform; troponin I, fast-twitch skeletal muscle isoform; troponin I, skeletal, fast; troponin I type 2 (skeletal, fast); Troponin I, fast-twitch isoform], [TNNI2; TNNI2; DA2B; FSSV; fsTnI; AMCD2B] |
Gene, Accession # | [TNNI2], Gene ID: 7136, NCBI: NP_003273.1 |
Catalog # | MBS416039 |
Price | $230 |
Order / More Info | TNNI2 Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Li,Y., Chen,B., Chen,J., et al. Fast skeletal muscle troponin I is a co-activator of estrogen receptor-related receptor alpha. Biochem. Biophys. Res. Commun. 369 (4), 1034-1040 (2008). |