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Antigenic Specificity | BRAF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BRAF: v-raf murine sarcoma viral oncogene homolog B1, also known as BRAF1; RAFB1; B-RAF1; FLJ95109. Entrez Protein NP_004324. It is the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway. B-Raf contains three consensus Akt phosphorylationsites (Ser364, Ser428, and Thr439). B-Raf is a key regulatory molecule of the mitogen-activated protein kinase kinase (MEK), it has a long amino-terminal region,the region is essential for homo-dimerization of B-Raf and hetero-dimerization of B-Raf and c-Raf at the plasma membrane, followed by phosphorylation of Thr118 in the amino-terminal B-Raf-specific region. Notably, in calcium ionophore-stimulated HeLa cells, B-Raf could propagate signals to MEK under the basal level of G |
Immunogen | Immunogen: A synthetic peptide of human BRAF Calculated Molecular Weight: 84kDa |
Other Names | [BRAF1; RAFB1; B-RAF1; FLJ95109; NS7], [BRAF; BRAF; NS7; BRAF1; RAFB1; B-RAF1; BRAF1; RAFB1] |
Gene, Accession # | [BRAF], Gene ID: 673, NCBI: P15056.4, UniProt: P15056 |
Catalog # | MBS126633 |
Price | $200, $275, $430 |
Order / More Info | BRAF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |