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Antigenic Specificity | Mouse IL-17A |
Clone | [TC11-18H10.1] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1, kappa |
Format | fluorescein (FITC) conjugate |
Size | 20 tests, 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-kappaB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 w |
Immunogen | n/a |
Other Names | [Interleukin-17A; IL-17; IL-17A; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8; CTLA8] |
Gene, Accession # | [IL-17A], Gene ID: 16171, NCBI: NP_034682.1, UniProt: Q62386 |
Catalog # | MBS2559457 |
Price | $70, $85, $100 |
Order / More Info | Mouse IL-17A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |