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Antigenic Specificity | MRE11 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MRE11 Polyclonal Antibody detects endogenous levels of MRE11 protein. MRE11A encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. Double-strand break repair protein MRE11A forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alt |
Immunogen | Immunogen: Synthesized peptide derived from human MRE11 around the non-phosphorylation site of S264 |
Other Names | [Rabbit MRE11; MRE11A; HNGS1; MRE11; Double-strand break repair protein MRE11A; Meiotic recombination 11 homolog 1; MRE11 homolog 1; Meiotic recombination 11 homolog A; MRE11 homolog A] |
Gene, Accession # | [MRE11], Gene ID: 4361, NCBI: NP_005581.2, UniProt: P49959 |
Catalog # | MBS9702512 |
Price | $130, $220, $325 |
Order / More Info | MRE11 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |