IL2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIL2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous level of total IL2 protein. IL-2 is a T cell stimulatory cytokine best known for inducing T cell proliferation and NK cell proliferation and activation (1,2). IL-2 also promotes peripheral development of Treg cells (4, 5). Conversely, IL-2 is involved in activation induced cell death (AICD) that is observed post T cell expansion by increasing levels of Fas on CD4+ T cells (3). The effects of IL-2 are mediated through a trimeric receptor complex consisting of IL-2Ra, IL-2Rb and the common gamma chain, gc (1,2). IL-2 Ra binds exclusively to IL-2 with low affinity and increases binding affinity of the whole receptor complex including IL-2Rb and gc subunits. IL-2Rb is also used by IL-15 (1,2). The common gc is us
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human IL2.
Other Names[IL2; IL-2; TCGF; lymphokine]
Gene, Accession #[IL2], Gene ID: 3558, NCBI: NP_000577.2, UniProt: P60568
Catalog #MBS9402476
Price$255
Order / More InfoIL2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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