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Antigenic Specificity | IL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total IL2 protein. IL-2 is a T cell stimulatory cytokine best known for inducing T cell proliferation and NK cell proliferation and activation (1,2). IL-2 also promotes peripheral development of Treg cells (4, 5). Conversely, IL-2 is involved in activation induced cell death (AICD) that is observed post T cell expansion by increasing levels of Fas on CD4+ T cells (3). The effects of IL-2 are mediated through a trimeric receptor complex consisting of IL-2Ra, IL-2Rb and the common gamma chain, gc (1,2). IL-2 Ra binds exclusively to IL-2 with low affinity and increases binding affinity of the whole receptor complex including IL-2Rb and gc subunits. IL-2Rb is also used by IL-15 (1,2). The common gc is us |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human IL2. |
Other Names | [IL2; IL-2; TCGF; lymphokine] |
Gene, Accession # | [IL2], Gene ID: 3558, NCBI: NP_000577.2, UniProt: P60568 |
Catalog # | MBS9402476 |
Price | $255 |
Order / More Info | IL2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |