Phospho-STAT3 (Tyr705) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-STAT3 (Tyr705)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemisty (IHC), Immunoflurescene (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), ELISA (EIA)
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DescriptionSpecificity: Phospho-STAT3 (Tyr705) antibody detects endogenous levels of STAT3 only when phosphorylated at Tyrosine 705. Description: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo-or heterodimers that translocate to the cell nucleus where they act as transcription activators.Function: Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors (PubMed:10688651, PubMed:12359225, PubMed:12873986, PubMed:15194700, PubMed:17344214, PubMed:18242580, PubMed:23084476). Once activated, recruits coactivator
ImmunogenImmunogen: A synthesized peptide derived from human STAT3 around the phosphorylation site of Tyrosine 705 Subcellular Location: Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm. Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4. Constitutive nuclear presence is independent of tyrosine phosphorylation. Predominantly present in the cytoplasm without stimuli. Upon leukemia inhibitory fac
Other Names[1110034C02Rik; Acute Phase Response Factor; Acute-phase response factor; ADMIO; APRF; AW109958; DNA binding protein APRF; FLJ20882; HIES; MGC16063; Signal transducer and activator of transcription 3 (acute phase response factor); Signal transducer and activator of transcription 3; STAT 3; Stat3; STAT3_HUMAN]
Gene, Accession #[STAT3], Gene ID: 6774, NCBI: NP_003141.2, UniProt: P40763
Catalog #MBS9601062
Price$240, $280
Order / More InfoPhospho-STAT3 (Tyr705) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesBai Y, Wang J, Han J, Xie XL, Ji CG, Yin J, Chen L, Wang CK, Jiang XY, Qi W, Jiang HQ; Journal: Mol Carcinog. BCL2L10 inhibits growth and metastasis of hepatocellular carcinoma both in vitro and in vivo. Yu L, Wang S, Lin X, Lu Y, Gu P; Journal: Mol Med Rep. MicroRNA-124a inhibits cell proliferation and migration in liver cancer by regulating interleukin-11. Wu Y, Xu J, Xu J, Zheng W, Chen Q, Jiao D; Journal: Mol Med Rep. Study on the mechanism of JAK2/STAT3 signaling pathway-mediated inflammatory reaction after cerebral ischemia.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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