Advanced glycosylation end product-specific receptor Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAdvanced glycosylation end product-specific receptor
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatcaprylic acid ammonium sulfate precipitate
Size0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous level of total Advanced glycosylation end product-specific receptor polyclonal antibody. Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation,
ImmunogenImmunogen: Recombinant Human Advanced glycosylation end product-specific receptor protein
Other Names[Receptor for advanced glycosylation end products; AGER; RAGE]
Gene, Accession #Gene ID: 177, NCBI: NP_001127.1, UniProt: Q15109
Catalog #MBS9415259
Price$320
Order / More InfoAdvanced glycosylation end product-specific receptor Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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