Edit |   |
Antigenic Specificity | Apolipoprotein B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Apolipoprotein B-100(APOB) detection. Background: Apolipoprotein B (ApoB) is a protein that in humans is encoded by the APOB gene. This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mu |
Immunogen | Immunogen: E. coli-derived human Apolipoprotein B recombinant protein (Position: Q246-N450). Human Apolipoprotein B shares 82.4% and 80.5% amino acid (aa) sequence identity with mouse and rat Apolipoprotein B, respectively. |
Other Names | [Apo B-100; ApoB 100; Apo B-48; ApoB 48; APOB; Apolipoprotein B 100; Apolipoprotein B; Apolipoprotein B-48; Apolipoprotein B48; FLDB; LDLCQ4; P04114], [APOB; APOB; FLDB; LDLCQ4; apoB-48; apoB-100; Apo B-100; Apo B-48] |
Gene, Accession # | [APOB], Gene ID: 338, NCBI: NP_000375.2, UniProt: P04114 |
Catalog # | MBS178798 |
Price | $315 |
Order / More Info | Apolipoprotein B Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Jacobson TA (2011). Opening a new lipid apo-thecary: incorporating apolipoproteins as potential risk factors and treatment targets to reduce cardiovascular risk. Mayo Clinic Proceedings 86 (8): 762-780.2. Lim JS, Lee DH, Park JY, Jin SH, Jacobs DR (2011). Reliability of low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and apolipoprotein B measurement.Journal of Clinical Lipidology 5 (4): 264-272. |