CASP3 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-CASP3 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CASP3 |
| Clone | [1262CT521.280.101] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.48 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Purified His-tagged CASP3 protein was used to produced this monoclonal antibody. Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. |
| Immunogen | n/a |
| Other Names | [Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12; CASP3; CPP32] |
| Gene, Accession # | [CASP3], Gene ID: 836, NCBI: NP_004337.2, UniProt: P42574 |
| Catalog # | MBS9200553 |
| Price | $165, $370 |
| Order / More Info | CASP3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Choudhary C., et al. Science 325:834-840(2009). Fernandes-Alnemri T., et al. J. Biol. Chem. 269:30761-30764(1994). Tewari M., et al. Cell 81:801-809(1995). Pelletier M., et al. Biochem. Biophys. Res. Commun. 316:93-99(2004). Ota T., et al. Nat. Genet. 36:40-45(2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies