Mouse KLRG1/MAFA-LE/AF Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse KLRG1/MAFA-LE/AF |
| Clone | [2F1] |
| Host Species | Syrian Hamster |
| Reactive Species | mouse, human |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | n/a |
| Applications | Flow Cytometry; Immunoprecipitation |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Mouse/Human KLRG1; Mr 30-38 kDa. The monoclonal antibody 2F1 reacts with mouse killer cell lectin-like receptor G1 (KLRG1; formerly known as mouse MAFA or 2F1-Ag), a homodimeric member of the lectin-like type 2 transmembrane receptor family that contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains.1, 2 These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1.3, 4 The 2F1 antibody stains 30-60% of NK1.1+CD3- splenocytes, and a small fraction of T cells in all mouse strains tested (C57BL/6, BALB/c, 129/J, C3H.SW, AKR/J, SJL).1, 5 Cell surface expression of KLRG1 is up-regulated by expression of MHC class I molecules. The effect of MHC class I expression |
| Immunogen | Immunogen: IL-2-activated NK cells (A-LAK cells) from B6 (H-2b) mice |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS673580 |
| Price | $365 |
| Order / More Info | Mouse KLRG1/MAFA-LE/AF Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Corral, L., T. Hanke, R.E. Vance, D. Cado, and D.H. Raulet. 2000. Eur. J. Immunol. 30:920.2. Hanke, T., L. Corral, R.E., Vance, and D.H. Raulet. 1998. 28:4409.3. Burshtyn, D., A. Scharenberg, N. Wagtmann, S. Rajagopalan, M. Peruzzi, J.-P. Kinet, and E.O. Long. 1997. Immunity 4:77.4. Nakamura, M.C., E.C. Niemi, M.J. Fisher, L.D. Schultz, W.E. Seaman, and J.C. Ryan. 1997. J. Exp. Med. 185:673.5. Liu, S., and D.H. Raulet. Personal communication. |
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MYBIOSOURCE INC.
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