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Antigenic Specificity | CLCF1 (N-term), 46-72 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CLCF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-72 amino acids from the N-terminal region of human CLCF1. This gene is a member of the glycoprotein (gp)130 cytokinefamily and encodes cardiotrophin-like cytokine factor 1 (CLCF1).CLCF1 forms a heterodimer complex with cytokine receptor-likefactor 1 (CRLF1). This dimer competes with ciliary neurotrophicfactor (CNTF) for binding to the ciliary neurotrophic factorreceptor (CNTFR) complex, and activates the Jak-STAT signalingcascade. CLCF1 can be actively secreted from cells by forming acomplex with soluble type I CRLF1 or soluble CNTFR. CLCF1 is apotent neurotrophic factor, B-cell stimulatory agent and |
Immunogen | n/a |
Other Names | [Cardiotrophin-like cytokine factor 1; B-cell-stimulating factor 3; BSF-3; Novel neurotrophin-1; NNT-1; CLCF1; BSF3; CLC; NNT1] |
Gene, Accession # | [CLCF1], Gene ID: 23529, NCBI: NP_001159684.1, UniProt: Q9UBD9 |
Catalog # | MBS9206438 |
Price | $165, $370 |
Order / More Info | CLCF1 (N-term), 46-72 Antibody from MYBIOSOURCE INC. |
Product Specific References | Rousseau, F., et al. J. Biol. Chem. 283(44):30341-30350(2008) Dagoneau, N., et al. Am. J. Hum. Genet. 80(5):966-970(2007) Rousseau, F., et al. Proc. Natl. Acad. Sci. U.S.A. 103(26):10068-10073(2006) Perret, D., et al. J. Biol. Chem. 279(42):43961-43970(2004) Burger, R., et al. Br. J. Haematol. 123(5):869-878(2003) |