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Antigenic Specificity | RBBP4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Retinoblastoma-associated proteins 46 and 48 (RBAP46 and RBAP48; also known as RBBP7 and RBBP4) were first characterized in human cells as proteins that bind to the retinoblastoma (Rb) tumor suppressor protein (1). Since then, these proteins have been shown to be components of many protein complexes involved in chromatin regulation, including the chromatin assembly factor 1 (CAF-1) complex and type B histone acetyltransferase complex HAT1, both of which function in chromatin assembly during DNA replication (2, 3). RBAP46 and RBAP48 are also found in the nucleosome remodeling factor complex NURF, the nucleosome remodeling and histone de-acetylation complex NuRD, and the Sin3/HDAC histone de-acetylation complex (4-7). More recently, RBAP46 an |
Immunogen | Immunogen: Recombinant protein of human RBBP4 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [NURF55; RBAP48] |
Gene, Accession # | [RBBP4], Gene ID: 5928, NCBI: NP_001128727.1, UniProt: Q09028 |
Catalog # | MBS8503454 |
Price | $310 |
Order / More Info | RBBP4 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Qian, Y.W. et al. (1993) Nature 364, 648-52. 2. Verreault, A. et al. (1996) Cell 87, 95-104. 3. Verreault, A. et al. (1998) Curr Biol 8, 96-108. 4. Barak, O. et al. (2003) EMBO J 22, 6089-100. 5. Zhang, Y. et al. (1999) Genes Dev 13, 1924-35. 6. Zhang, Y. et al. (1997) Cell 89, 357-64. 7. Kuzmichev, A. et al. (2002) Genes Dev 16, 2893-905. 8. Cao, R. et al. (2002) Science 298, 1039-43. |