SMURF1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-SMURF1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | SMURF1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: SMURF1 antibody is human, mouse and rat reactive. At least three isoforms of SMURF1 are known to exist this antibody will recognize all three isoforms. SMURF1 is predicted to not cross-react with SMURF2. SMURF1 (SMAD ubiquitin regulatory factor 1) is a negative regulator of TGF-beta signaling (1). SMURF1 and SMURF2 are members of HECT domain E3 ubiquitin ligase which are involved in the enzymatic reactions of the Ub conjugating pathway (1,2). SMURF1 negatively regulates osteoblast activity and response to bone morphogenesis protein (BMP) through controlling MEKK2 degradation (3). SMURF1 has recently been shown to play a role in breast cancer cell migration and invasion through the downregulation of RhoA (4). |
| Immunogen | Immunogen: SMURF1 antibody was raised against a 16 amino acid peptide near the amino terminus of human SMURF1. Buffer: SMURF1 antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [SMAD specific E3 ubiquitin protein ligase 1; SMAD ubiquitination regulatory factor 1; E3 ubiquitin-protein ligase SMURF1; SMAD specific E3 ubiquitin protein ligase 1], [SMURF1; SMURF1; KIAA1625; hSMURF1] |
| Gene, Accession # | [SMURF1], Gene ID: 57154, NCBI: NP_065162 |
| Catalog # | MBS153727 |
| Price | $375 |
| Order / More Info | SMURF1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies