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Antigenic Specificity | MEK5 |
Clone | [1F9-F3-B6] |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. UniPort Summary Function: Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical ro |
Immunogen | Immunogen: Purified recombinant fragment of human MAP2K5 (AA: 63-180) expressed in E Coli. Sequence Similarities: Contains 1 protein kinase domain. |
Other Names | [Dual specificity mitogen activated protein kinase kinase 5; Dual specificity mitogen-activated protein kinase kinase 5; EC 2.7.12.2; HsT17454; MAP kinase kinase 5; MAP kinase kinase MEK5b; MAP2K5; MAPK/ERK kinase 5; MAPKK 5; MAPKK5; MEK 5; mitogen-activated protein kinase kinase 5; MKK5; MP2K5_HUMAN; PRKMK5; Protein kinase, mitogen-activated, kinase 5; SAPKK5; SKK5], [MAP2K5; MEK5; MAPKK5; PRKMK5; HsT17454] |
Gene, Accession # | [MEK5], Gene ID: 5607, NCBI: NP_001193733.1, UniProt: Q13163 |
Catalog # | MBS476556 |
Price | $335 |
Order / More Info | MEK5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |