IGF1R (Phospho-Tyr1346) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-IGF1R (Phospho-Tyr1346) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | IGF1R (Phospho-Tyr1346) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of IGF1R only when phosphorylated at tyrosine 1346. This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.Ullrich A., EMBO J. 5:2503-2512(1986).Abbot A.M., J. Biol. Chem. 267:10759-10763(1992).The MGC Project Team;Genome Res. 14:2121-2127(2004). |
| Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 1346(Q-P-Y(p)-A-H) derived from Human IGF1R. |
| Other Names | [CD221; kinase IGF1R; IGF1R] |
| Gene, Accession # | [IGF1R], Gene ID: 3480, NCBI: NP_000866.1, UniProt: P08069 |
| Catalog # | MBS9406331 |
| Price | $200, $255 |
| Order / More Info | IGF1R (Phospho-Tyr1346) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies