c-Fos Antibody from MYBIOSOURCE INC.

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Antigenic Specificityc-Fos
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration0.2 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionRabbit anti c-Fos antibody recognizes c-Fos also known as G0/G1 switch regulatory protein 7 (G0S7). The c-Fos transcription factor is encoded by the c-Fos proto-oncogene and dimerizes with c-Jun, JDP and ATF family members to form the AP-1 transcription factor (Eferl and Wagner 2003). c-Fos plays an essential role in mediating cellular signaling responses after cellular stress. The ability of the c-Fos protein to act as a transcription factor is regulated by phosphorylation on selected sites by the kinases p38, ERK, RSK1 and RSK2 (Lopez-Bergami et al. 2011). The protein accumulates in the nucleus, where it acts as a transcription factor upon formation of heterodimers with c-Jun. This binding prevents the nuclear export and subsequent proteo
ImmunogenImmunogen: Peptide mapping to the amino terminus of human c-Fos
Other Names[c-Fos], [FOS; FOS; p55; AP-1; C-FOS; G0S7]
Gene, Accession #[FOS], Gene ID: 2353, NCBI: P01100.1, UniProt: P01100
Catalog #MBS225055
Price$375
Order / More Infoc-Fos Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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