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Antigenic Specificity | c-Fos |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.2 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti c-Fos antibody recognizes c-Fos also known as G0/G1 switch regulatory protein 7 (G0S7). The c-Fos transcription factor is encoded by the c-Fos proto-oncogene and dimerizes with c-Jun, JDP and ATF family members to form the AP-1 transcription factor (Eferl and Wagner 2003). c-Fos plays an essential role in mediating cellular signaling responses after cellular stress. The ability of the c-Fos protein to act as a transcription factor is regulated by phosphorylation on selected sites by the kinases p38, ERK, RSK1 and RSK2 (Lopez-Bergami et al. 2011). The protein accumulates in the nucleus, where it acts as a transcription factor upon formation of heterodimers with c-Jun. This binding prevents the nuclear export and subsequent proteo |
Immunogen | Immunogen: Peptide mapping to the amino terminus of human c-Fos |
Other Names | [c-Fos], [FOS; FOS; p55; AP-1; C-FOS; G0S7] |
Gene, Accession # | [FOS], Gene ID: 2353, NCBI: P01100.1, UniProt: P01100 |
Catalog # | MBS225055 |
Price | $375 |
Order / More Info | c-Fos Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |