USP7 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-USP7 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | USP7 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Ubiquitinating enzymes (UBEs) catalyze protein ubiquitination, a reversible process countered by deubiquitinating enzyme (DUB) action (1, 2). Five DUB subfamilies are recognized, including the USP, UCH, OTU, MJD and JAMM enzymes. Herpesvirus-associated ubiquitin-specific protease (HAUSP, USP7) is an important deubiquitinase belonging to USP subfamily. A key HAUSP function is to bind and deubiquitinate the p53 transcription factor and an associated regulator protein Mdm2, thereby stabilizing both proteins (3, 4). In addition to regulating essential components of the p53 pathway, HAUSP also modifies other ubiquitinylated proteins such as members of the FoxO family of forkhead transcription factors and the mitotic stress checkpoint protein CHF |
| Immunogen | Immunogen: Recombinant protein of human USP7 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [USP7; HAUSP; TEF1] |
| Gene, Accession # | [USP7], Gene ID: 7874, NCBI: NP_001308787.1, UniProt: Q93009 |
| Catalog # | MBS8503394 |
| Price | $310 |
| Order / More Info | USP7 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Nijman, S.M. et al. (2005) Cell 123, 773-86. 2. Nalepa, G. et al. (2006) Nat Rev Drug Discov 5, 596-613. 3. Li, M. et al. (2002) Nature 416, 648-53. 4. Brooks, C.L. et al. (2007) Oncogene 26, 7262-6. 5. van der Horst, A. et al. (2006) Nat Cell Biol 8, 1064-73. 6. Oh, Y.M. et al. (2007) Biochem Biophys Res Commun 357, 615-9. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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