Alpha Actinin 4/ACTN4 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Alpha Actinin 4/ACTN4 |
| Clone | [93] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The spectrin gene family encodes a diverse group of cytoskeletal proteins that include spectrins, dystrophins and -actinins. There are four tissue-specific -actinins, namely -actinin-1, -actinin-2, -actinin-3 and -actinin-4, which are localized to muscle and non-muscle cells, including skeletal, cardiac and smooth muscle cells, as well as within the cytoskeleton. Each -actinin protein contains one Actin-binding domain, two calponin-homology domains, two EF-hand domains and four spectrin repeats, through which they function as bundling proteins that can cross-link F-Actin, thus anchoring Actin to a variety of intracellular structures. Defects in the gene encoding -actinin-4 are the cause of focal segmental glomerulosclerosis 1 (FSGS1), a com |
| Immunogen | Immunogen: Recombinant full-length human ACTN4 protein |
| Other Names | [F-actin cross-linking protein; Focal segmental glomerulosclerosis 1 (FSG1); Non-muscle alpha-actinin-4] |
| Gene, Accession # | [ACTN4], Gene ID: 81, NCBI: O43707.2, UniProt: O43707 |
| Catalog # | MBS4381356 |
| Price | $190, $340, $340 |
| Order / More Info | Alpha Actinin 4/ACTN4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Krusius, T. and Ruoslahti, E. 1986. Proc. Natl. Acad. Sci. USA 83: 7683-7687. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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