PRKCD Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | PRKCD |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Activation of protein kinase C (PKC) is one of the earliest events in a cascade that controls a variety of cellular responses, including secretion, gene expression, proliferation, and muscle contraction (1,2). PKC isoforms belong to three groups based on calcium dependency and activators. Classical PKCs are calciumdependent via their C2 domains and are activated by phosphatidylserine (PS), diacylglycerol (DAG), and phorbol esters (TPA, PMA) through their cysteine-rich C1 domains. Both novel and atypical PKCs are calciumin-dependent, but only novel PKCs are activated by PS, DAG, and phorbol esters (3-5). Members of these three PKC groups contain a pseudo-substrate or autoinhibitory domain that binds to substrate-binding sites in the catalyti |
| Immunogen | Immunogen: A synthetic -peptide of human PRKCD |
| Other Names | [PRKCD; PKCd; PRKCD; MAY1; MGC49908; PKCD; nPKC-delta; Protein kinase C delta type; nPKC-delta; PKCdelta;], [PRKCD; PRKCD; MAY1; PKCD; nPKC-delta; SDK1] |
| Gene, Accession # | Gene ID: 5580, NCBI: NP_006245.2, UniProt: Q05655 |
| Catalog # | MBS125748 |
| Price | $200, $275, $430 |
| Order / More Info | PRKCD Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Nishizuka, Y. (1984) Nature 308, 693-698. 2. Keranen, L.M. et al. (1995) Curr. Biol. 5, 1394-1403. 3. Mellor, H. and Parker, P.J. (1998) Biochem J. 332 (Pt 2), 281-292. 4. Ron, D. and Kazanietz, M.G. (1999) FASEB J. 13, 1658-1676. 5. Moscat, J. and DiazMeco, M.T. (2000) EMBO Rep. 1, 399-403. 6. Baron, C.L. and Malhotra, V. (2002) Science 295, 325-328. 7. Flynn, P. et al. (2000) J. Biol. Chem. 275, 11064-11070. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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