Neurofilament (H+L) (Neuronal Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNeurofilament (H+L) (Neuronal Marker)
Clone[NF421 + NFL/736]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat, chicken, porcine
IsotypeIgG1
Formatunconjugated
Sizen/a
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunohistochemistry (IHC) Formalin
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DescriptionThis MAb reacts with a 200kDa and 68kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H & NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of
ImmunogenImmunogen: Recombinant human neurofilament protein
Other Names[NEFH; Neurofilament H; Neurofilament Heavy Polypeptide 200kDa; Neurofilament Triplet H Protein; NF-H; NF200. 68kDa neurofilament protein, Light molecular weight neurofilament protein, NEFL, Neurofilament light polypeptide 68kDa, Neurofilament light polypeptide, Neurofilament protein, light chain, Neurofilament subunit NF-L, Neurofilament triplet L protein, NF-L, NF68], [NEFL]
Gene, Accession #[NEFH], Gene ID: 4744, NCBI: NP_066554.2, UniProt: P12036
Catalog #MBS438818
Priceplease inquire
Order / More InfoNeurofilament (H+L) (Neuronal Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesIshii M et. al. Fukushima J Med Sci. 2004;50(2):65-74. Angelides, K.J., et. al. 1989. J. Cell Biol. 108: 1495-1506.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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