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Antigenic Specificity | REG3A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Regenerating islet-derived protein 3-alpha (REG3A), also known as hepatocarcinoma-intestine-pancreas/ pancreatitis-associated protein (HIP/PAP), is a secreted intestinal antimicrobial protein that functions in the control of the bacterial proliferation. It is normally expressed in pancreatic acinar and endocrine cells. REG3A is highly expressed in keratinocytes during psoriasis and wound repair and in imiquimod-induced psoriatic skin lesions. The expression of REG3A by keratinocytes is induced by interleukin-17 (IL-17) via activation of keratinocyte-encoded IL-17 receptor A (IL-17RA) and feeds back on keratinocytes to inhibit terminal differentiation and increase cell proliferation by binding to exostosin-like 3 (EXTL3). REG3A stimulates Be |
Immunogen | Immunogen Information: A full length recombinant REG3A protein was used as the immunogen for this antibody. |
Other Names | [REG3A; HIP; PAP; PAP1; Hepatointestinal pancreatic protein; Human proislet peptide; Pancreatitis-associated protein 1; Reg III-alpha; Regenerating islet-derived protein III-alpha; to REG3A; REG3A; REG3A], [REG3A; REG3A; HIP; PAP; PAP1; REG3; INGAP; PAP-H; PBCGF; HIP/PAP; REG-III; HIP; PAP; PAP1; REG-3-alpha; HIP/PAP; Reg III-alpha] |
Gene, Accession # | [REG3A], Gene ID: 5068, NCBI: Q06141.1, UniProt: Q06141 |
Catalog # | MBS668766 |
Price | $140, $270 |
Order / More Info | REG3A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |