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Antigenic Specificity | Bcl-2 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). |
Immunogen | Immunogen: A synthesized peptide derived from human Bcl-2. Subcellular Localization: Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. Tissue Specificity: Expressed in a variety of tissues. |
Other Names | [Apoptosis regulator Bcl-2; BCL2], [BCL2] |
Gene, Accession # | [Bcl-2], Gene ID: 596, NCBI: NP_000624.2, UniProt: P10415 |
Catalog # | MBS179053 |
Price | $160, $340, $340 |
Order / More Info | Bcl-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |