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Antigenic Specificity | 14-3-3 BETA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, human, mouse, rabbit, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item recognises the acetylated N-terminal of 14-3-3 beta. It is a member of the 14-3-3 family which consists of 30 kDa proteins that are involved in multiple protein kinase signalling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3 show distinct preference for it's different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein. . . 14-3-3 beta plays a role in the pathogenesis of systemic lupus erythematosus and is involved in negative regulation of p90 ribosomal S6 kinase activity and tuberous sclerosis tumour suppressor proteins. It also binds IGF-1 receptor, RAF1 and CDC25 phosphatases. . |
Immunogen | Immunogen: Synthetic peptide corresponding to acetylated N-terminal sequence of sheep 14-3-3 beta. Peptide sequence: Ac.TMDKSELVC Histology Positive Control Tissue: Normal brain tissue Antiserum Preparation: Antisera to sheep 14-3-3 beta were raised by repeated immunisations of rabbit with highly purified antigen. Target Species: Sheep |
Other Names | [14-3-3 protein beta/alpha; 14-3-3 protein beta/alpha; Protein kinase C inhibitor protein 1; KCIP-1], [YWHAB; KCIP-1] |
Gene, Accession # | [14-3-3 BETA], NCBI: P68251.2, UniProt: P68251 |
Catalog # | MBS222329 |
Price | $375 |
Order / More Info | 14-3-3 BETA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |