Mouse ST2 (N-TERMINAL) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse ST2 (N-TERMINAL)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size0.1 mg
ConcentrationIgG concentration 1.0mg/ml
ApplicationsWestern Blot (WB)
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DescriptionRabbit anti Mouse ST2 (N-Terminal) antibody recognizes an epitope within the N-Terminal region (NT) of mouse ST2, a member of the Toll-interleukin 1 receptor (TIR) superfamily, expressed by mast cells and TH2 helper cells, but not by TH1 effector cells. The majority of TIR superfamily members, which includes the Interleukin-1 receptor (IL-1R1), Toll-like receptors (TLRs) and the cytosolic adaptor proteins MyD88, TIRAP, Trif and TRAM, initiate innate immunity through the ultimate activation of the transcription factor NF-kappaB and are inducers of the inflammatory response. In contrast ST2, which itself is unable to activate NF-kappaB, has been identified as a negative regulator of IL-1R1 and TLR4 signaling by sequestering MyD88 and TIRAP in
ImmunogenImmunogen: A 16 amino acid synthetic peptide located near mouse ST2 amino-terminus. This peptide is common to the three known isoforms of ST2. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to mouse ST2 (NT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Mouse
Other Names[interleukin-1 receptor-like 1 isoform a; Interleukin-1 receptor-like 1; interleukin-1 receptor-like 1; lymphocyte antigen 84; interleukin 1 receptor-like 1; Lymphocyte antigen 84; Protein ST2; Protein T1], [Il1rl1; Il1rl1; T1; St2; DER4; Ly84; ST2L; Fit-1; T1/ST2; St2-rs1; Ly84; St2; Ste2]
Gene, Accession #[ST2], Gene ID: 17082, NCBI: NP_001020773.1, UniProt: P14719
Catalog #MBS221876
Price$375
Order / More InfoMouse ST2 (N-TERMINAL) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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