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Antigenic Specificity | Mouse ST2 (N-TERMINAL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Mouse ST2 (N-Terminal) antibody recognizes an epitope within the N-Terminal region (NT) of mouse ST2, a member of the Toll-interleukin 1 receptor (TIR) superfamily, expressed by mast cells and TH2 helper cells, but not by TH1 effector cells. The majority of TIR superfamily members, which includes the Interleukin-1 receptor (IL-1R1), Toll-like receptors (TLRs) and the cytosolic adaptor proteins MyD88, TIRAP, Trif and TRAM, initiate innate immunity through the ultimate activation of the transcription factor NF-kappaB and are inducers of the inflammatory response. In contrast ST2, which itself is unable to activate NF-kappaB, has been identified as a negative regulator of IL-1R1 and TLR4 signaling by sequestering MyD88 and TIRAP in |
Immunogen | Immunogen: A 16 amino acid synthetic peptide located near mouse ST2 amino-terminus. This peptide is common to the three known isoforms of ST2. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to mouse ST2 (NT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Mouse |
Other Names | [interleukin-1 receptor-like 1 isoform a; Interleukin-1 receptor-like 1; interleukin-1 receptor-like 1; lymphocyte antigen 84; interleukin 1 receptor-like 1; Lymphocyte antigen 84; Protein ST2; Protein T1], [Il1rl1; Il1rl1; T1; St2; DER4; Ly84; ST2L; Fit-1; T1/ST2; St2-rs1; Ly84; St2; Ste2] |
Gene, Accession # | [ST2], Gene ID: 17082, NCBI: NP_001020773.1, UniProt: P14719 |
Catalog # | MBS221876 |
Price | $375 |
Order / More Info | Mouse ST2 (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |