Phospho-rat TSC1 (S312) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Phospho-rat TSC1 (S312) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.32 |
| Applications | Dot Blot (DB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This rat TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S312 of rat TSC1. In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity). |
| Immunogen | n/a |
| Other Names | [Hamartin; Tuberous sclerosis 1 protein homolog; Tsc1] |
| Gene, Accession # | [Tsc1], Gene ID: 60445, NCBI: NP_068626.1, UniProt: Q9Z136 |
| Catalog # | MBS9200715 |
| Price | $165, $370 |
| Order / More Info | Phospho-rat TSC1 (S312) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Inoue, H., et al. Biosci. Biotechnol. Biochem. 73(11):2488-2493(2009) Di Nardo, A., et al. J. Neurosci. 29(18):5926-5937(2009) Chen, P., et al. Exp. Mol. Pathol. 86(2):101-107(2009) Momose, S., et al. Biochem. Biophys. Res. Commun. 356(3):693-698(2007) Goncharova, E., et al. J. Cell Biol. 167(6):1171-1182(2004) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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