Human ERYTHROPOIETIN RECEPTOR Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human ERYTHROPOIETIN RECEPTOR |
| Clone | polyclonal |
| Host Species | Sheep |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item recognises Erythropoietin Receptor (EPOR), a type I transmembrane protein and member of the type I cytokine receptor family, expressed by erythroid cells and erythroid progenitor cells, which acts as a receptor for erythropoietin (EPO) to mediate erythroblast proliferation and differentiation, and maintain progenitor survival. Binding of EPO to EPOR, results in the dimerization of the EPOR and the triggering of the JAK2/STAT5 signaling cascade, and in some cell types activation of STAT1 and STAT3. Several isoforms of EPOR exist: EPOR-F, EPOR-S and EPOR-T, and a functional EPOR is found on endothelial cells and cardiomyocytes within the cardiovascular system, suggesting a role in cardiac function. This item has been shown to block |
| Immunogen | Immunogen: Partial cDNA of the extracellular domain of human EPOR expressed as a GST fusion protein in E Coli. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antiserum to human EPOR was raised by repeated immunisation of sheep with highly purified antigen. Purified IgG was prepared by affinity chromatography. Target Species: Human |
| Other Names | [erythropoietin receptor; Erythropoietin receptor; erythropoietin receptor; erythropoietin receptor], [EPOR; EPOR; EPO-R; EPO-R] |
| Gene, Accession # | Gene ID: 2057, NCBI: NP_000112.1 |
| Catalog # | MBS224081 |
| Price | $300 |
| Order / More Info | Human ERYTHROPOIETIN RECEPTOR Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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