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Antigenic Specificity | ARG2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated CD4+ and CD8+ T cells (PubMed:27745970). May suppress inflammation-related signaling in asthmatic airway epithelium (PubMed:27214549). May contribute to the immune evasion of H.pylori by restricting M1 macrophage activation and polyamine metabolism. In fetal dendritic cells may play a role in promoting immune suppression and T cell TNF-alpha producti |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-354 of human ARG2 (NP 001163.1). |
Other Names | [arginase-2, mitochondrial; Arginase-2, mitochondrial; arginase-2, mitochondrial; arginase 2; Kidney-type arginase; Non-hepatic arginase; Type II arginase] |
Gene, Accession # | [ARG2], Gene ID: 384, NCBI: NP_001163.1, UniProt: P78540 |
Catalog # | MBS8546036 |
Price | $280 |
Order / More Info | ARG2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |