ATG5 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | ATG5 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents (1, 2). Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer (3). The molecular machinery of autophagy was largely discovered in yeast and referred to as autophagy-related (Atg) genes. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles (4-6). This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10 (7, 8). |
| Immunogen | Immunogen: Recombinant protein of human ATG5 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [ATG5; APG5; APG5-LIKE; APG5L; ASP; hAPG5] |
| Gene, Accession # | [ATG5], Gene ID: 9474, NCBI: NP_001273035.1, UniProt: Q9H1Y0 |
| Catalog # | MBS8505000 |
| Price | $310 |
| Order / More Info | ATG5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Reggiori, F. and Klionsky, D.J. (2002) Eukaryot Cell 1, 11-21. 2. Codogno, P. and Meijer, A.J. (2005) Cell Death Differ 12 Suppl 2, 1509-18. 3. Levine, B. and Yuan, J. (2005) J Clin Invest 115, 2679-88. 4. Mizushima, N. et al. (1998) J Biol Chem 273, 33889-92. 5. Mizushima, N. et al. (1998) Nature 395, 395-8. 6. Suzuki, K. et al. (2001) EMBO J 20, 5971-81. 7. Tanida, I. et al. (1999) Mol Biol Cell 10, 1367-79. 8. Shintani, T. et al. (1999) EMBO J 18, 5234-41. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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