PHLPP2, NT Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPHLPP2, NT
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatammonium sulfate precipitate
Size0.2 mL
Concentrationn/a
ApplicationsELISA (EL/EIA), Western Blot (WB)
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DescriptionRecognizes human PHLPP2. PHLPP2 is a protein phosphatase that specifically mediates dephosphorylation of 'Ser-473' of AKT1. This protein regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decrease cell proliferation. It also controls the phosphorylation of AKT3.
ImmunogenImmunogen: Synthetic peptide corresponding to aa11-40 from the N-terminal region of human PHLPP2 conjugated to KLH.
Other NamesPHLPP2, NT (PH Domain Leucine-rich Repeat-containing Protein Phosphatase 2, KIAA0931, PH Domain Leucine-rich Repeat-containing Protein Phosphatase-like, PHLPP-like, PHLPPL)
Gene, Accession #Gene ID: 23035, NCBI: NP_055835.2, UniProt: Q6ZVD8
Catalog #MBS628170
Price$610
Order / More InfoPHLPP2, NT Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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