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Antigenic Specificity | PHLPP2, NT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | ammonium sulfate precipitate |
Size | 0.2 mL |
Concentration | n/a |
Applications | ELISA (EL/EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human PHLPP2. PHLPP2 is a protein phosphatase that specifically mediates dephosphorylation of 'Ser-473' of AKT1. This protein regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decrease cell proliferation. It also controls the phosphorylation of AKT3. |
Immunogen | Immunogen: Synthetic peptide corresponding to aa11-40 from the N-terminal region of human PHLPP2 conjugated to KLH. |
Other Names | PHLPP2, NT (PH Domain Leucine-rich Repeat-containing Protein Phosphatase 2, KIAA0931, PH Domain Leucine-rich Repeat-containing Protein Phosphatase-like, PHLPP-like, PHLPPL) |
Gene, Accession # | Gene ID: 23035, NCBI: NP_055835.2, UniProt: Q6ZVD8 |
Catalog # | MBS628170 |
Price | $610 |
Order / More Info | PHLPP2, NT Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |