MLK1/2 (Phospho-Thr312/266) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMLK1/2 (Phospho-Thr312/266)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of MLK1/2 only when phosphorylated at threonine 312/266. The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.Durkin J.T., Biochemistry 43:16348-16355(2004).The MGC Project Team; Genome Res. 14:2121-2127(2004).Dorow D.S.,Nature 446:153-158(2007).
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of threonine 312/266(A-G-T(p)-Y-A) derived from Human MLK1/2.
Other Names[M3K9; PRKE1; mixed-lineage protein kinase 1]
Gene, Accession #[MLK1/2], Gene ID: 4293, NCBI: NP_001271159.1, UniProt: P80192
Catalog #MBS9414936
Price$200, $255
Order / More InfoMLK1/2 (Phospho-Thr312/266) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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