TNFR1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TNFR1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: TNFR1 antibody detects endogenous levels of TNFR1. Description: TNF-R1 Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. Binding of TNF to the extracellular domain leads to homotrimerization. The aggregated death domains provide a novel molecular interface that interacts specifically with the death doma |
| Immunogen | Immunogen: A synthesized peptide derived from human TNFR1 Subcellular Location: Cell Membrane. Golgi Apparatus Membrane. Secreted. A secreted form is produced through proteolytic processing and secreted. Lacks a golgi-retention motif, is not membrane bound and therefore is secreted. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog Similarity: Pig (92%), Bovine (100%), Horse (100%), Rabbit (83%), Dog (100%) |
| Other Names | [CD120a; FPF; MGC19588; p55; p55-R; p60; TBP1; TBPI; TNF R; TNF R55; TNF-R1; TNF-RI; TNFAR; TNFR-I; TNFR1; TNFR55; TNFR60; TNFRI; TNFRSF1a; TNR1A_HUMAN; Tumor necrosis factor receptor 1; Tumor necrosis factor receptor superfamily, member 1A; Tumor necrosis factor receptor type 1; Tumor necrosis factor receptor type I; Tumor necrosis factor-binding protein 1] |
| Gene, Accession # | [TNFR1], Gene ID: 7132, NCBI: NP_001056.1, UniProt: P19438 |
| Catalog # | MBS9600219 |
| Price | $240, $280 |
| Order / More Info | TNFR1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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