Edit |   |
---|---|
Antigenic Specificity | TTF1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity). |
Immunogen | Immunogen: A synthesized peptide derived from human TTF1. Subcellular Localization: Nucleus. Tissue Specificity: Thyroid and lung. |
Other Names | [Homeobox protein Nkx-2.1; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; TTF-1; Thyroid-specific enhancer-binding protein; T/EBP; NKX2-1; NKX2A; TITF1; TTF1], [NKX2-1] |
Gene, Accession # | [TTF1], Gene ID: 7080, NCBI: NP_001073136.1, UniProt: P43699 |
Catalog # | MBS179627 |
Price | $160, $340, $340 |
Order / More Info | TTF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |