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Antigenic Specificity | Mouse NOTCH 1 |
Clone | [mN1A] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Immunohistology Frozen, Flow cytometry (FC/FACS)*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Mouse Notch 1 antibody, clone mN1A specifically recognizes Notch 1, one of the four major transmembrane receptors (Notch 1-4) of the Notch signalling pathway, which is activated through binding to DSL domain-containing membrane-bound specific ligands. The Notch signalling pathway is an evolutionarily conserved pathway in multi-cellular organisms, which is vital for cell-cell communication, important during fundamental developmental and physiological processes, including regulation of cell fate decisions during neuronal, cardiac and endocrine development, stem cell haematopoiesis, thymic T-cell development, and both tumour progression and suppression. Ligation of Notch receptors by their specific ligands, Jagged1 (CD339), Jagged2, |
Immunogen | n/a |
Other Names | [neurogenic locus notch homolog protein 1; Neurogenic locus notch homolog protein 1; neurogenic locus notch homolog protein 1; Motch A; Notch gene homolog 1; mT14; major type A protein; p300; transmembrane receptor Notch1; notch 1; Motch A; mT14; p300Cleaved into the following 2 chains:Notch 1 extracellular truncation; NEXT; Notch 1 intracellular domain; NICD], [Notch1; Notch1; N1; Mis6; Tan1; lin-12; 9930111A19Rik; Motch; Notch 1; NEXT; NICD] |
Gene, Accession # | [NOTCH 1], Gene ID: 18128, NCBI: NP_032740.3, UniProt: Q01705 |
Catalog # | MBS212783 |
Price | $300 |
Order / More Info | Mouse NOTCH 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |