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Antigenic Specificity | Phospho-PIK3R1/2/3-Y467 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1./Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding Y467 of human PIK3R1/2/3 Calculated Molecular Weight: 85kDa |
Other Names | [Phospho-PIK3R1/PIK3R2/PIK3R3-Y467: PI3-kinase p85 subunit alpha; PtdIns-3-kinase p85-alpha], [PIK3R1; PIK3R1; p85; AGM7; GRB1; IMD36; p85-ALPHA; GRB1; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha] |
Gene, Accession # | [PIK3R1/PIK3R2/PIK3R3], Gene ID: 5295, NCBI: P27986.2, UniProt: P27986 |
Catalog # | MBS128300 |
Price | $235, $350, $525 |
Order / More Info | Phospho-PIK3R1/2/3-Y467 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |