Phospho-GSK3B (Ser9) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-GSK3B (Ser9)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshumanpredicted: mouse, rat, Xenopus
Isotypen/a
Formatunconjugated
Size0.05 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis Phospho-GSK3B (Ser9) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2-33 amino acids from human GSK3B. Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. Requires primed phosphorylation of the majority of its substrates. In skeletal muscle, contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. May also mediate the
Immunogenn/a
Other Names[Glycogen synthase kinase-3 beta; GSK-3 beta; 2.7.11.26; Serine/threonine-protein kinase GSK3B; 2.7.11.1; GSK3B]
Gene, Accession #[GSK3B], Gene ID: 2932, NCBI: NP_001139628.1, UniProt: P49841
Catalog #MBS9231105
Price$165, $370
Order / More InfoPhospho-GSK3B (Ser9) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesStambolic V.,et al.Biochem. J. 303:701-704 (1994). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Lau K.F.,et al.Genomics 60:121-128 (1999). Rhoads A.R.,et al.Mol. Psychiatry 4:437-442 (1999). Boyle W.J.,et al.Cell 64:573-584 (1991).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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