THEM4 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-THEM4 antibody, protein, ELISA kits.
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| Antigenic Specificity | THEM4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The additional higher molecular weight bands seen in the immunoblot may represent post-translationally modified TMEM4. THEM4, also known as CTMP, binds specifically to the carboxy-terminal regulatory domain of PKB/Akt at the plasma membrane and acts as a negative regulator, reversing the phenotype of v-Akt-transformed cells. Hypermethylation of the THEM4 promoter and transcriptional downregulation of the gene has been reported in multiple glioblastomas, suggesting that epigenetic regulation of THEM4 may play a role in the progression of this cancer. Bioinformatic analysis, confirmed by in vitro testing, indicates that THEM4 is a broad-range, high activity acyl-CoA thioesterase. Recent reports have also indicated that TMEM4 is a mitochondria |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against an 18 amino acid peptide near the center of human THEM4. |
| Other Names | [Thioesterase superfamily member 4, Carboxy-terminal modulator protein, CTMP] |
| Gene, Accession # | [THEM4], Gene ID: 117145, NCBI: NP_444283 |
| Catalog # | MBS9409381 |
| Price | $320 |
| Order / More Info | THEM4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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