BSG Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBSG
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionBasigin (EMMPRIN, CD147) is a type I integral membrane receptor protein belonging to the immunoglobulin superfamily (1). Basigin is a glycosylated protein with four known isoforms, of which isoform 2 is the most abundantly expressed (2). Multiple functions have been ascribed to Basigin; foremost among these is stimulating the secretion of extracellular matrix metalloproteinases by adjacent fibroblasts, a function which has been implicated in promoting tumor progression (2-4). Research studies have shown that Basigin is overexpressed by many tumor cells, and its expression level may correlate with tumor malignancy (5, 6). A recent study identified the BASIGIN gene as a regulatory target of Slug, suggesting a role for Basigin in the process o
ImmunogenImmunogen: Recombinant protein of human BSG Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[5F7; CD147; EMMPRIN; M6; OK; TCSF]
Gene, Accession #[BSG], Gene ID: 682, NCBI: NP_001309172.1, UniProt: P35613
Catalog #MBS8504979
Price$310
Order / More InfoBSG Antibody from MYBIOSOURCE INC.
Product Specific References1. Biswas, C. et al. (1995) Cancer Res 55, 434-9. 2. Liao, C.G. et al. (2011) Mol Cell Biol 31, 2591-604. 3. Sweeny, L. et al. (2012) Exp Cell Res 318, 1788-98. 4. Lescaille, G. et al. (2012) BMC Cancer 12, 115. 5. Piao, S. et al. (2012) J Cancer Res ClinOncol 138, 627-35. 6. Bi, X.C. et al. (2011) Clin Invest Med 34, E358. 7. Wu, J. et al. (2011) Oncogene 30, 4410-27. 8. Solstad, T. et al. (2011) Blood 118, 5141-51. 9. Crosnier, C. et al. (2011) Nature 480, 534-7.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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