NEDD4L - middle region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NEDD4L - middle region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This is a rabbit polyclonal antibody against NEDD4L. It was validated on Western Blot using a cell lysate as a positive control.Target Description: NEDD4L is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. NEDD4L inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. NEDD4L promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. NEDD4L also promotes ubiquitination and degradation of SGK. |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NEDD4L |
| Other Names | [E3 ubiquitin-protein ligase NEDD4-like isoform 3; E3 ubiquitin-protein ligase NEDD4-like; E3 ubiquitin-protein ligase NEDD4-like; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase; HECT-type E3 ubiquitin transferase NED4L; NEDD4.2; Nedd4-2] |
| Gene, Accession # | [NEDD4L], Gene ID: 23327, NCBI: NP_056092, UniProt: Q96PU5 |
| Catalog # | MBS3206756 |
| Price | $365 |
| Order / More Info | NEDD4L - middle region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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