CASP7 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CASP7 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CASP7 antibody detects endogenous levels of total CASP7. Description: Caspase-7 (CMH-1, Mch3, ICE-LAP3) has been identified as a major contributor to the execution of apoptosis (1-4). Caspase-7, like caspase-3, is an effector caspase that is responsible for cleaving downstream substrates such as (ADP-ribose) polymerase and PARP (1, 3). During apoptosis, caspase-7 is activated through proteolyticprocesssing by upstream caspases at Asp23, Asp198, and Asp206 to produce the mature subunits (1, 3). Similar to caspases-2 and-3, caspase-7 preferentially cleaves substrates following the recognition sequence DEVD (5).Function: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates s |
| Immunogen | Immunogen: A synthesized peptide derived from human CASP7 Subcellular Location: Cytoplasmic Tissue Specificity: Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (90%), Bovine (100%), Horse (90%), Sheep (100%), Rabbit (100%), Dog (100%) |
| Other Names | [Apoptotic protease Mch-3; Apoptotic protease MCH3; CASP-7; CASP7; CASP7_HUMAN; Caspase 7; Caspase 7 apoptosis related cysteine peptidase; Caspase-7 subunit p11; Caspase7; CMH 1; CMH-1; CMH1; ICE LAP3; ICE-LAP3; ICE-like apoptotic protease 3; LICE2; MCH3] |
| Gene, Accession # | [CASP7], Gene ID: 840, NCBI: NP_001218.1, UniProt: P55210 |
| Catalog # | MBS9607098 |
| Price | $240, $280 |
| Order / More Info | CASP7 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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