PKC-theta (N-terminal region) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PKC-theta (N-terminal region) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, rat, mouse |
| Isotype | IgG2a |
| Format | Protein A purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody detects a 79 kDa* protein corresponding to the molecular mass of PKCq on SDS-PAGE immunoblots of human Jurkat cell lysates. The Protein Kinase C (PKC) family of homologous serine/threonine protein kinases is involved in a number of processes such as growth, differentiation, and cytokine secretion. At least eleven isozymes have been described. PKC consists of a single polypeptide chain containing four conserved regions (C) and five variable regions (V). The N-terminal half interacts with PKC activators Ca2+, phospholipid, diacylglycerol, or phorbol ester, while the C-terminal half contains the catalytic domain. The conventional PKC subfamily (a, bI, bII, and g) is regulated by both Ca2+ and diacylglycerol. The PKC pathway repre |
| Immunogen | Immunogen: Clone (M217) was generated from a recombinant mouse PKCq protein that included amino acids residues in the N-terminal region. This sequence is conserved in human and rat PKCq, and has low homology to other PKC family members. |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS470025 |
| Price | $325 |
| Order / More Info | PKC-theta (N-terminal region) Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Kawakami et al. (2003) Proc. Natl. Acad. Sci. USA 100:9470-9475.• Nishizuka, Y. (1988) Nature 334:661. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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