SRRT (N-term), 54-81 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SRRT (N-term), 54-81 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: bovine, mouse) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This SRRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-81 amino acids from the N-terminal region of human SRRT. SRRT acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and RNASEN, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer ars |
| Immunogen | n/a |
| Other Names | [Serrate RNA effector molecule homolog; Arsenite-resistance protein 2; SRRT; ARS2; ASR2] |
| Gene, Accession # | [SRRT], Gene ID: 51593, NCBI: NP_001122324.1, UniProt: Q9BXP5 |
| Catalog # | MBS9204861 |
| Price | $165, $370 |
| Order / More Info | SRRT (N-term), 54-81 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Eijgelsheim, M., et al. Hum. Mol. Genet. 19(19):3885-3894(2010) Kiriyama, M., et al. Mol. Cell. Biol. 29(17):4729-4741(2009) Gruber, J.J., et al. Cell 138(2):328-339(2009) Wilson, M.D., et al. Mol. Cell. Biol. 28(5):1503-1514(2008) Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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