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Antigenic Specificity | CBP |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CBP Antibody detects endogenous levels of CBP. CBP a protein acetyltransferase that can transcriptionally activate histones. Acetylates the NCOA3 coactivator. Binds specifically to phosphorylated CREB1 and enhances its transcriptional activity toward cAMP-responsive genes. Methylation of the KIX domain by CARM1 blocks association with CREB, blocking CREB signaling, and activating the apoptotic response. Found in a complex containing NCOA2, NCOA3, IKKA, IKKB, and IKBKG. Probably part of a complex with HIF1A and EP300. Interacts with the C-terminal region of CITED4. The TAZ-type 1 domain interacts with HIF1A. Interacts with MAF, SRCAP, CARM1, ELF3, MLLT7/FOXO4, N4BP2, NCOA1, NCOA3, NCOA6, PCAF, PELP1, PML, SMAD1, SMAD2, SMAD3, SP |
Immunogen | Immunogen: A synthesized peptide derived from human CBP |
Other Names | [CBP; CREB binding protein; CREB-binding protein; CREBBP; KAT3A; RSTS] |
Gene, Accession # | [CBP], Gene ID: 1387, NCBI: NP_001073315.1, UniProt: Q92793 |
Catalog # | MBS8511149 |
Price | $290 |
Order / More Info | CBP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |