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Antigenic Specificity | ARHGEF7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, monkey |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions. May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ARHGEF7 (NP 001106984.1). |
Other Names | [P50; P85; PAK3; PIXB; COOL1; P50BP; COOL-1; P85SPR; BETA-PIX; P85COOL1; Nbla10314] |
Gene, Accession # | [ARHGEF7], Gene ID: 8874, NCBI: NP_001106983.1, UniProt: Q14155 |
Catalog # | MBS8544237 |
Price | $280 |
Order / More Info | ARHGEF7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |