Edit |   |
---|---|
Antigenic Specificity | VAV3 (Phospho-Tyr173) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of VAV3 only when phosphorylated at tyrosine 173. This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.Trenkle T., Nucleic Acids Res. 26:3883-3891(1998).Movilla N., Mol. Cell. Biol. 19:7870-7885(1999). |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 173 (E-V-Y(p)-E-D) derived from Human VAV3. |
Other Names | [VAV3; FLJ40431; Guanine nucleotide exchange factor VAV3] |
Gene, Accession # | [VAV3], Gene ID: 10451, NCBI: NP_001073343.1, UniProt: Q9UKW4 |
Catalog # | MBS9411512 |
Price | $200, $255 |
Order / More Info | VAV3 (Phospho-Tyr173) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |