TEAD2 (Center), 267-295 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TEAD2 (Center), 267-295 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This TEAD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-295 amino acids from the Central region of human TEAD2. Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epi |
| Immunogen | n/a |
| Other Names | [Transcriptional enhancer factor TEF-4; TEA domain family member 2; TEAD-2; TEAD2; TEF4] |
| Gene, Accession # | [TEAD2], Gene ID: 8463, NCBI: NP_001243587.1, UniProt: Q15562 |
| Catalog # | MBS9214650 |
| Price | $165, $370 |
| Order / More Info | TEAD2 (Center), 267-295 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Tian, W., et al. Proc. Natl. Acad. Sci. U.S.A. 107(16):7293-7298(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Zhang, H., et al. J. Biol. Chem. 284(20):13355-13362(2009) Zhao, B., et al. Genes Dev. 22(14):1962-1971(2008) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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