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Antigenic Specificity | JAK2 |
Clone | [9B4] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | Protein A purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 1mg/mL |
Applications | Immunohistochemistry (IHC) Paraffin (IHC-p) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Non-receptor tyrosine kinase involved in various processes such as cell cycle progression, apoptosis, mitotic recombination, genetic instability and histone modifications. In the cytoplasm, plays a pivotal role in signal transduction via its association with cytokine receptors, which constitutes an initiating step in signaling for many members of the cytokine receptor superfamily including the receptors for growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), granulocyte-macrophage colony-stimulating factor (CSF2), thrombopoietin (THPO) and multiple interleukins. Following stimulation with erythropoietin (EPO) during erythropoiesis, it is autophosphorylated and activated, leading to its association with erythropoiet |
Immunogen | Immunogen: Synthetic Peptide of JAK2 Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Other Names | [Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)] |
Gene, Accession # | [JAK2], Gene ID: 3717, NCBI: NP_001309123.1, UniProt: O60674 |
Catalog # | MBS2549028 |
Price | $110, $150, $225 |
Order / More Info | JAK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |