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Antigenic Specificity | ELL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ELL antibody detects endogenous levels of total ELL. Function: Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically required for stimulating the elongation step of RNA polymerase II-and III-dependent snRNA gene transcription (PubMed:23932780). ELL also plays an early role before its assembly into in the SEC complex by stabilizing |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus Tissue Specificity: Expressed in all tissues tested. Highest levels found in placenta, skeletal muscle, testis and peripheral blood leukocytes. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Dog, Chicken, Xenopus Similarity: Pig (91%), Zebrafish (100%), Bovine (91%), Horse (100%), Dog (100%), Chicken (100%), Xenopus (100%) |
Other Names | [eleven nineteen lysine rich leukemia gene; Eleven-nineteen lysine-rich leukemia protein; ELL1; elongation factor RNA polymerase II; Men; RNA polymerase II elongation factor] |
Gene, Accession # | [ELL], Gene ID: 8178, NCBI: NP_006523.1, UniProt: P55199 |
Catalog # | MBS9604679 |
Price | $240, $280 |
Order / More Info | ELL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |